Olde Scooter's Favorite Theory of Aging
(Theory Belief/Hope about) Aging Itself The Geroscience Hypothesis Duff, another of your rants on senolytics? In a nutshell: Aging is caused by many things, but the buildup of senescent cells as we age is one that is both a CAUSE and and EFFECT of aging. Circular, no? As time goes by, compounding damage happens to cells that causes them to become senescent -- no more dividing and replicating but they don't die, they just hang around and emit SASP* which has inflammatory and other nasty molecules that speed up that long slide to death by "natural causes."** Old people build up a LOT of senescent cells. They weaken the immune system that clears them out in younger people, more circular deterioration. GETTING RID OF SENESCENT CELLS WILL POSTPONE THAT. ` As I read more about it, I started blasting out blog posts in late 2017 . I was smitten by this paragraph: “Aging is the main risk factor for many chronic degenerative diseases and cancer. Increased senescent cell burd