SeniorJunior

ANOTHER KIND OF A I. (I've done this numerous time over the looong course of this blogging hobby.  Gone All In with something. I'm All In on worrying about the troll/bot cyber war, All In on getting worried about China passing us all over the place, All In on piping water from the wet east to the dry west of this country, AI on global warming, AI on evolution explaining everything, AI on AI... on and on. At least once it's been embarrassingly wrong, but hey...)  Now I'm going All In on SENOLYTICS. (Meaning I'll do several more posts whooping up any new findings.) UpDate  (article in Science Magazine - the cancer angle) Update 2 I like"It's conceivable" statements. “It is conceivable that the rapidly emerging repertoire of senolytic agents might  transform medicine as we know it.” ... says  James L. Kirkland MD, PhD  of Mayo Clinic (guy on lower left.*) Things are just getting rolling big time on finding and testing senolytic drugs

For Sure When You Shop Walmart,  Harbor Freight.. .      ...and many, MANY more retail stores.              And stuff on AMAZON... Whoo Boy! I'm the 80%-er. Piker. I'm the 92%-er. Approximately 80% of Walmart’s suppliers are still located in China, we’ll let the facts speak for themselves . Approximately 92% of all products sold at Harbor Freight are made in China. * China Makes 50% Of All Your Stuff: Popular Science The price rises will sneak up on you. "Where is all our money going?" will be a frequently asked question among us of the non-rich tribe. (The Richie Rich Tribe won't notice.) The long term impact on the overall American economy is uncertain; certainly the "experts" are. To quote President Trump: "We'll see. We'll see." Speaking of politics, Politico has this :   Trump’s trade wars start biting GOP ahead of midterms Who knows?  Not me, for sure. *Estimate made after exte

There Was My Favorite Toy Ever (when I was 10) The Lone Ranger Atomic Bomb Ring ! I have a scintillating personality!  I had one . Five Kix boxtops (I loved Kix, no problem) and a bit of change and I had my very own Spinthariscope. Take off the red tail fins, get in a dark place and look in the little l ens... ...and you could see scintillation, tiny tracks of atomic particle activity. Oh the thrill. Apparently none of us Lone Ranger radio show fans suffered any radiation damage.  I'm told. My ring finger only glows very slightly. VERY slightly. Funky site

For a Brief Time My Worries were Salved.  The salve was in a cute tube of American bravado But Now.... we get this headline in the authoritative Aviation Week newsletter: U.S. Hypersonics Face Uphill Struggle To Match China, Russia Sep 21, 2018 Guy Norris    |  Aerospace Daily & Defense Report I'll sneak around you and come up from behind  before you even know I'm on the way. This is not good. In the balance-of-power thing, America should have parity at the very minimum in these important, fist-of-the-gods weapons. Traditionally, we have the lead in the Big Scaries. The way of the world is that you can't rest on your laurels in any competition. The game proceeds. Michael Griffin, the Pentagon’s new undersecretary of defense for research and engineering , spake on the problem: “The U.S. has been taking a decade-long holiday from the exigencies of great power competition,” so we're seriously behind in a few vital fields. One is he

They Feel Threatened, I reckoned... Careful, I'm tougher than I look. And these guys are getting out their Righteous Sticks, and are ready to whop some sense into those pushy... ... skirts. One pal of mine - a professional and affluent white guy in his sixties (WAY younger than me) - has been writing diatribes about #MeToo, et al. Now the Judge Kavanaugh kerfuffle has pushed him closer to the edge. He sees a catastrophic attack on God's Order re men and women .   I asked him if he felt threatened or what else might account for stuff like him writing the "New Women's Bill of Rights" with an attempt at humor, but you could hear his teeth grinding.  Stuff like: Amendment VIII Excessive bail shall not be required, no excessive fines imposed,  nor cruel and unusual punishments inflicted,  unless they are men (Maybe he didn't write it, just plagiarized it, which I hope since it's grammatical nonsense.) He sent me a single line response.

Look at All Those "Likes!" I'm a LikeBot . I like what I'm programmed to like. Really like it a lot ! When a troll comment pops up, a LIKEBOT, programmed to support the troll, jumps in and registers a "like."  Then it notifies more LIKEBOTS with accounts of their own, and they pump up the likes, like LIKEBOTS like to do. It works best when there are a few real "likes."  Like all good lies, there are usually strains of truth in them. We the gullible see this and think whatever nasty thing the troll said is very "popular;" lots of people like it. And, hey, I sort of like it too, even though it's over the line. So woweee, Batman, I've been moved further toward the crazy zone and further away from people I disagree with. The polarization disease spreads. For every fake account harboring a bot that Facebook, Twitter, Instagram, et al remove from their platforms, another - maybe five others - register and start bott

Forbes, the fanboy magazine for billionaire$...  ...had two " SENOLYTIC " pieces on Sept  24. I'm betting most of the rich people read both of them: 40,993 views Sep 24, 2018, 02:16am Senolytic Therapies Seem To Stop Alzheimer's Disease 'In Its Tracks' Robin Seaton Jefferson And... 4,745 views Sep 24, 2018, 02:16am Senolytic Therapies And The Quest To Cure Aging Robin Seaton Jefferson I posit the proposition (har, har) that ALL rich people are interested in living the longest, healthiest lives money can buy.  Lo, I have held forth thereon. So that was one reason they all read both pieces. The other of course can be heard in, "Alexa, buy a bloc of common in the following pharmaceuticals." Always looking for an edge of any kind.  Those darn rich people. This is good for us in the lower 95% Having an affluent, eager crowd of customers just waiting for the new product

Never Pass a Chance to Beat Your Favorite Drum Hey, Y'all. Look out for Trolls and Bots! I was reading the "Comments" section after a review of Ms. Daniels' new book, Full Disclosure , in the Washington Post .  Lo and behold, my expert Troll/Bot spotting eyes saw quite a few. So I fired up my favorite motor scooter and scooted right in with this: duffworx Herein is a great collection of reader comments. It's the perfect place to look for Russian/Iranian/N.Korean, et al Troll/bots. WaPo, imho, is under high volume troll attacks in the Comments space because there is not much high level moderating.  Trolls all over! HOW TO SPOT 'EM: Remember a standard attack mode (to create the  social chaos called 'polarization') is to escalate the hyperbole on BOTH sides of the GAS (Great American Split). I say 'remember' because a lot of people still think those cyber warriors are all Trumpsters, alt-righters, etc.  Not so!  Here at t

See? I Told You to Bone Up on Senolytics [OK, this is more mouse research... but exciting!] Published Wednesday, 19 September in Nature Magazine ... one of the Super Journals (meaning they are as credible as they come, science-journal-wise), a paper based on research done at Mayo Clinic , a pretty good outfit.   Published:  19 September 2018 Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline If you keep up on Alzheimer's research, you recognize "tau-dependent," and if you don't, you surely know about cognitive decline. That and memory loss are the heart-ripping Alzheimer's symptoms we'd all like to avoid.  If You Are Interested in the Science Put your science hat on and take a look at the abstract (free) in Nature . Or read a (also free) layperson version.  Here's a short one (written for Big Pharma money men).                                                                  Here's a lo

While You Are Praying for the Carolinas...          ...Say one for the Philippines AMEN Credit  

The Nose / Gut / Brain Boogie Just a touch of my favorite subject, from the bottomless well of academia. Peddling influence, like everybody else See?  I've been telling you* stuff like this: (Go ahead, have a linking extravaganza.) Recent studies have focused on the role of gut microbiota in modulation of the enteric and central nervous system functions, including behaviour (Bravo  et al .,  2011 ; Foster & McVey Neufeld,  2013 ; Mayer, Tillisch & Gupta,  2015 ; Forsythe  et al .,  2016 ; Sarkar  et al .,  2016 ). This rapidly emerging field employs classical psychological tests of behaviour to begin to understand better how the gut microbiome and the brain interact in health and in models of disease (Collins,  2014 ; Mayer  et al .,  2015 ; Sarkar  et al .,  2016 ). Many of these tests involve assessment of social behaviour and interaction (Tarr  et al .,  2015 ; McKim  et al .,  2016 ; Bharwani  et al .,  2017 ,  2016 ) and it has come to our attention onl

OK, I'm mad.  REALLY mad. This is the last straw to me. President Trump's war on the climate is a  grossly irresponsible travesty of governing. Loosening the rules and allowing more methane leakage into the air, just to "reverse another Obama policy" and please Big Oil and Big Gas... OUGHT TO  BE A CRIME. Methane is many times more potent than CO2 as a heat trapping gas. Surely you've noticed how I trap heat when you emit me? Giant Los Angeles methane leak in infra red. We are GasFlare 1 and GasFlare 2 (with flames). GF3 there is just spewing Methane. We're all BAAAD! You know how methane smells? That's the way this latest climate atrocity smells to me. I encourage you to raise a stink over this one. Just one wound infected with this poison. Graphic Credit Flare  Pix Credit

Just snipped this from the Airedale subReddit    If you say this is photoshopped, I'll lick you to death. Airdales  über alles !

SINGAPORE? For the last few days, it's been Germany. That's weird enough, but today it's.... No telling what blog I read. I have only made one post on this manifold blog that was specifically about Singapore, and that was back in 2010. Here 'tis. And yet... and yet...  SEPTEMBER 7, 2018 daily report 4PM MST Entry Pageviews Singapore 435 France 99 Germany 32 United States 23 Poland 4 United Kingdom 3 Indonesia 1 Romania 1 Turkey 1 From my Blogger account; Audience report.  No pattern to the pageviews. 'Tis a mystery. Anyway, HOWDY to anyone in Singapore who might be around.  p.s. And you French folk, bonsoir!